Which condition is characterized by hematuria, hearing loss, and is X-linked?

Alport's syndrome is characterized by a triad of symptoms, which includes hematuria, hearing loss, and lens dislocation, with the most significant and distinguishing feature being its X-linked inheritance pattern. This genetic condition arises from mutations in collagen type IV, which is crucial for the structural integrity of the basement membranes in various tissues, including the kidneys, ears, and eyes.

In Alport's syndrome, hematuria is typically one of the first symptoms to present, often detected during routine urinalysis. As the disease progresses, patients commonly experience progressive kidney disease, leading to renal failure. Hearing loss, particularly sensorineural, occurs due to the abnormalities affecting the cochlea of the inner ear, while visual disturbances can arise from associated ocular anomalies.

The other listed conditions do not share this specific combination of symptoms and inheritance pattern. For instance, Wegener's granulomatosis (now known as Granulomatosis with polyangiitis) is an autoimmune condition primarily affecting the respiratory system and kidneys but does not typically present with X-linked inheritance or hearing loss. Goodpasture's syndrome involves an autoimmune attack on the lungs and kidneys but also lacks the prominent hearing loss and X-linked features. IgA nephropathy primarily presents